According to the CDC, every 40 seconds,
a person in the United States has a stroke, and every 4 minutes,
someone dies from one. It is the leading cause of disability and in
the top five causes of death. The scariest part about it is that
there may be no warning signs. A stroke happens suddenly with all of
its symptoms happening at exactly the same moment. So what is this
silent killer and what can be done to prevent it? A stroke is a lack
of blood flow to the brain, either due to a blockage of blood in an
artery or cranial hemorrhaging. When blood flow ceases, the brain
gets oxygen deprived. This can cause fainting, numbness, slurred
speech, loss of vision, and many other symptoms, depending on which
part of the brain is lacking oxygen. It can often result in brain
damage if the problem is not resolved.
Hemorrhagic strokes account for one
fifth of the total and due primarily to a faulty artery bursting in
the brain. The artery can be thought of as a balloon. The more the
balloon is blown up the more it gets stretched thin. Eventually just
blowing it up in its normal fashion will cause it to burst. This is
the same with the arteries in the brain. They get rubbed thin by
blood passing by them, especially if the blood is thick due to an
improper diet. Eventually, they rupture. This is called an aneurysm.
Hemorrhagic strokes are often linked with previous head trauma and
are the more dangerous of the two.
When the blood is blocked due to a
build up in the arteries, the oxygen-deprived parts of the brain shut
down. Sometimes the cases are so severe that the person must be
admitted to a hospital and given a clot-busting drug to restore blood
flow. Other times the build up of pressure behind the blockage is
enough to push the clump through the artery allowing more blood to
flow. When the blood is leaking out due to hemorrhaging, most often
the patient will need surgery.
The
most common surgeries are a intracranial or extracranial bypass and
carotid
endarterectomy. The bypass is a surgery used to reroute blood flow
away from a plaque-infested or blocked pathway. It's like if the were
in accident on the freeway and instead of clearing all the cars, they
just reroute them permanently through a detour. An endarterectomy, shown on the right, is
a procedure where surgeons remove build up of plaque. In this
situation, instead of rerouting cars, they simply take out some of
the slower cars to avoid any jam in the first place. After
a stroke, a person may need to be in rehabilitation for speech,
muscles, or work. If he or she was without oxygen for long enough
they can cause serious brain damage as well as muscle damage, if the
clot was formed elsewhere than the brain.
In either case, even after the blood
has been restored, the person is still at a high risk for another
stroke. In order to decrease the risk of another stroke, patients
often take medication to reduce their blood pressure including
diuretics, vasodilators, ACE inhibitors, beta blockers, and a variety
of others. The most common medication taken after a stroke is
aspirin, which reduces the platelet count. Platelets are the blood
cells that help in clotting. An aspirin a day has been shown to
reduce the chance of a stroke.
In order to prevent a stroke, it
doesn't hurt to take an aspirin a day, but the most important thing
is to eat right and keep blood pressure at a normal level. Eating
foods high in high-density cholestrols will help in the removal of
unwanted clumps in the blood stream. The best foods in this case are
ones that are not high in fat. This will also reduce the amount of
free fatty acids in the blood, which are the cause of
atherosclerosis. Eating healthy and going to the doctor often are the
best ways to live a healthy life.
“Aneurysms.”
A.D.A.M. Medical Encyclopedia, PubMed Health, 13 August 2010.
http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0002109/
Imholtz, Alex. “Blood Questions.”
Anatomy and Physiology at Prince George's Community College.
http://academic.pgcc.edu/~aimholtz/AandP/PracticeQuestions/Blood/bloodq2.html
“Relating
to Heart - Atoguard & Atoprin (Atenolol+Amlodipine+Aspirin).”
Perk, 2012.
http://www.perk.in/ato-guard-prin-folder-product-information.htm
“Stroke: Hope through Research.”
National Institute of Neurological Disorders and Stroke, 6 September
2012.
http://www.ninds.nih.gov/disorders/stroke/detail_stroke.htm#214271105
Images:
http://www.michiganstrokenetwork.com/Treatment/Overview/v/Hemorrhagic/patients.aspxOverview/v/Hemorrhagic/patients.aspx
http://www.vascularweb.org/vascularhealth/Pages/endarterectomy.aspx
http://www.perk.in/ato-guard-prin-folder-product-information.htm
I work in neurology lab, we study herpes viruses, mostly varicella zoster virus (VZV). We showed few years ago that VZV can cause stroke (ischemic stroke more likely, and other vasculopathies). After initial infection (chicken pox), the virus goes latent in trigeminal and dorsal root ganglia. Later in life in may reactive and and cause shigles or other problems including stoke. The virus reactivates from TGs, travels transaxonally into cerebral arteries. VZV infection in the arteries leads to thrombosis, necrosis, aneurysm, and dissection. CAs of patients who died of VZV vasculopathy were tested positive for VZV antigen and DNA. When VZV Vasculopathy is suspected, patient’s CSF is tested for VZV antigen and DNA and if it comes back positive, treatment with antiviral drugs such as aciclovir begins immediately. It’s important to understand that if the cause is VZV, than it’s treatable.
ReplyDeleteReference:
Nagel MA, Mahalingam R, Cohrs RJ, Gilden D. Virus vasculopathy and stroke: an under-recognized cause and treatment target. Infect Disord Drug Targets. 2010