Long term patients of Inflammatory Bowel Disease are
prone to worsening flare ups, chronic pain, and colon cancer. Over three
quarters of Crohn’s patients and over one fourth of ulcerative colitis patients
opt into surgery as either a temporary remedy or, if removing the entire colon,
as a cure.
In ulcerative colitis, patients have the option of
removing just the infected section of the colon or removing the entire colon
and rectum. In majority of cases, the entire colon and rectum are removed in a
colectomy. Originally the only option after this was to attach the small
intestine to the abdominal wall in a colostomy. The small intestine would then
deposit into a small bag. While odorless and easy to hide, there were obvious
concerns with the fecal bag. A new approach had an internal bag made up of
small intestine epithelium which acts as a rectum, holding stool until it can
be removed with a tube through the hole in the abdominal wall. The most recent
surgical procedure to be approved for ulcerative colitis patients is an
ileo-anal anastomosis, where the large intestine and rectum are fully removed
and the small intestine is connected directly to the anus where sphincters are still
able to regulate bowel movements normally. Some reported cases of inflammation
near the anastomosis indicate that left over rectal muscle remained, which can
still be affected by the ulcerative colitis. Some people still lack entire
regulation. The primary complaint is that without a large intestine, the stool
is never properly dried and patients report diarrhea, but this can be avoided
with a proper diet.
With Crohn’s disease, surgery is more of a temporary
remedy. Since it occurs throughout the entire G.I. tract, it is not as simple
as simply removing the diseased tissue. Even if the disease only shows up in
the colon originally, removal of the colon would not necessarily remove the
disease. Out of all the patients that opt into surgery, half of them will have
new lesions in previously healthy parts of the tract. The most common colectomy
done on Crohn’s patients is removal of the sigmoid section of the colon, because
this is the highest risk area for colon cancer and Crohn’s disease is known for
causing colon cancer. Other patients have sections of their small intestine
removed if the area is so inflamed that it is causing obstructions to the
stool. The primary surgery chosen by Crohn’s patients is to repair ulcerative
tissue. This involves removing the small area which has ruptured, cleaning out abscesses
and pus, and reattaching internal fistula.
Surgery is not what gastroenterologists go to first.
Because of its low overall success rate, patients are generally steered toward
medication until there are such problems as ruptured G.I. tract, hemorrhaging
or colon cancer.
“Bowel Diversion Surgeries: Ileostomy, Colostomy, Ileoanal Reservoir, and Continent Ileostomy” MedicineNet. http://www.medicinenet.com/bowel_diversion_surgery_ileostomy_colostomy/article.htm
“Inflammatory
Bowel Disease.” Center for Disease Control and Prevention, 15 July 2011.
http://www.cdc.gov/ibd/
Wax, Arnold. “Living with
Colostomy.” Colorectal Cancer Health Center, WebMD, 1 June 2012. http://www.webmd.com/colorectal-cancer/guide/living-colostomy
I’ve had family members with colostomy bags. Although them seem “odorless and easy to hide,” its much more challenging then you would expect. Not to mention it DOES smell pretty badly. They leak and are a giant pain so I can see why they are so many new alternatives in the making. In you blog you were talking about a new approach where you place an internal bag of epithelium that acts as a rectum. I understand that this is an internal device located in the abdomen but how can it be “removed through a tube.” In my mind I can’t picture how it would be any different then a colostomy bag on the inside instead sticking out in a bag. I found additional information on ileo- anal anastomosis but couldn’t really find anything about the epithelium that acts as a rectum. Do have any ideas on how specifically that device works?
ReplyDeleteAn ileo-anal reservoir procedure may be the best way to treat this issue
ReplyDelete